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CA - 125
Investigation Result Units Biological Reference Interval

CA - 125 9.67 U/mL < 35

• Sample Type : SERUM. • Method: ECLIA. • Note : This test is not recommended to screen Ovarian cancer in the general population. Patients with confirmed Ovarian cancer may show normal pre-treatment CA 125 levels. Hence this assay, regardless of level, should not be interpreted as absolute evidence for the presence or absence of malignant disease. The assay value should be used in conjunction with findings from clinical evaluation and other diagnostic procedures. • Clinical Use • 1. An aid in the management of Ovarian cancer patients. Preoperative CA 125 level of < 65 U /mL is associated with a significantly greater 5 year survival rate. 2. Monitor the course of disease in patients with Invasive epithelial ovarian cancer. 3. Detection of residual tumor in patients with Primary epithelial ovarian cancer who have undergone first line therapy. Persistent elevation of CA 125 levels after 3 cycles of therapy indicates a poor prognosis. • Increased Levels seen in Primary epithelial ovarian carcinoma, Healthy individuals ( 1-2 %), First trimester of pregnancy, Follicular phase of menstrual cycle, Non malignant conditions – Cirrhosis, Hepatitis, Endometriosis, Ovarian cysts, Pelvic Inflammatory disease, Non Ovarian malignancies - Endometrial, Pancreatic, Lung, Breast, Colorectal & other Gastrointestinal tumors. • Disclaimer : 1) The above result relate only to the specimens received and tested in laboratory and should be always correlate with clinical findings and other laboratory markers. 2) Improper specimen collection, handling,storage and transportation may result in false negative/Positive results.

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